How to reduce the appearance of pigmentation marks after acne

September 22, 2026

Dark spots, redness, post-acne marks: what part can azelaic acid and PDRN play?


You thought you had finally said goodbye to your breakouts… but the marks are still there?

Many people with acne-prone skin find that blemishes clear up faster than the traces they leave behind. Between post-acne marks, lingering redness and dark spots that seem to settle in for the long haul, getting back to an even complexion can take more patience than expected.

After summer, a holiday in the sun, or simply because of repeated inflammation, these marks often become even more visible. That is why certain actives used in K-Beauty are drawing growing interest today — in particular azelaic acid and PDRN.


In short 

Azelaic acid is an active used to help manage hyperpigmentation and post-acne marks.

PDRN is used in skincare to help keep skin hydrated and comfortable.

Combining these two ingredients can be worth considering for anyone dealing with redness, blemishes and an uneven complexion.

Some K-Beauty products have been formulated specifically to address these concerns.

Why do post-acne marks stick around? 

Post-acne hyperpigmentation is a complex lesion that appears as the skin heals, caused by excess melanin production or dilated blood vessels, leaving red or brown marks.

Factors that can make this worse include:

  • Heavy UV exposure
  • Touching or picking at spots
  • A weakened skin barrier
  • Repeated inflammation

Post-acne marks are often linked to inflammation and to increased melanin production after a breakout.

How does azelaic acid help soften dark spots?

Azelaic acid is commonly used to help even out the complexion and soften the look of dark spots.

This active is used in skincare to act on the melanin formation process. It is also a favourite in routines built for acne-prone skin.

Azelaic acid can help to:

  • Soften the look of dark spots
  • Visually even out the complexion
  • Help reduce the look of redness
  • Improve skin texture
  • Offer a mild exfoliating effect
  • Contribute to protection against oxidative stress thanks to its antioxidant properties

That is why it turns up so often in products aimed at post-acne marks.

Worth remembering: azelaic acid is often used to help even out the complexion and improve the look of post-acne marks.

Why is PDRN attracting so much interest in K-Beauty?

PDRN is mainly used to help keep skin comfortable, hydrated and visibly more even.

PDRN stands for Polydeoxyribonucleotide. This ingredient can be sourced from salmon or trout DNA, while some versions also use raw materials derived from microalgae.

In K-Beauty, PDRN is often paired with products aimed at skin that is:

  • Sensitive
  • Dry
  • Showing a loss of firmness
  • Fragile after certain aesthetic procedures

PDRN is frequently mentioned for its potential role in:

  • Maintaining hydration
  • Improving the look of skin texture
  • Skin comfort
  • Visually evening out the complexion
  • Supporting the processes associated with collagen synthesis

Unlike some exfoliating actives, PDRN is generally presented as an ingredient whose benefits are gradual and cumulative.

PDRN is often used to support hydration and to help keep skin looking more even.

Azelaic acid or niacinamide: what is the difference?

Both ingredients can contribute to a better-looking complexion, but their main roles are not the same.

Criterion Azelaic acid Niacinamide
Hyperpigmentation Often used to help soften the look of dark spots Can contribute to a more even-looking complexion
Redness Can help reduce the look of redness Can contribute to visually calming the skin
Uneven complexion Often used to even out the complexion Can help revive overall radiance

Azelaic acid is more associated with post-acne marks and dark spots, while niacinamide is often used for the skin’s overall balance.

Which K-Beauty option combines azelaic acid and PDRN?

Some formulas bring these two actives together to address spots, redness and skin texture at the same time.

Among the options available, Mary&May Spicule Azelaic PDRN Spot Cream 15g was designed for areas affected by blemishes and visible marks.

Mary&May Spicule Azelaic PDRN Spot Cream 15g

👀Discover the products

According to the information provided by the brand, this product was developed to help:

  • Manage visible redness
  • Soften the look of hyperpigmentation
  • Preserve the skin barrier
  • Improve skin texture
  • Support skin balance
  • Look after blemish-prone skin

How do you fit this kind of product into a routine?

Order of application (routine)

  • Basic order: Toner ➔ Serum / Essence ➔ Targeted cream (spot cream) ➔ Moisturiser
  • Once the serum has sunk into the whole face, apply the targeted cream in a thin layer on the areas concerned.

Step-by-step tips

  • Pat gently to help it sink in: Apply a small amount only on blemishes or dark spots, then press gently with your fingertips. The micro-needles (spicules) can cause irritation, so whatever you do, don’t rub the skin.
  • Start with evening use: Because of how the spicules work, it is best to start with one application in the evening. Once your skin is used to it, you can use it morning and evening, always making sure to apply sun protection in the morning.
  • Temporary tingling: The tingling sensation during the first few uses is a natural reaction linked to the actives being absorbed. Before makeup, wait for the tingling to settle, then apply foundation by patting lightly with a puff or a brush.

Recommended routine by concern

Concern Suggested routine
Blemishes and excess sebum Tea tree toner → targeted product
Dull complexion and dark spots Alternate with a vitamin C serum depending on how well your skin tolerates it
Sensitive or dry skin Follow with a cream containing ceramides or panthenol to protect the skin barrier

Good to know

  • A patch test is recommended before first use.
  • A slight tingling sensation can appear during the first few applications.
  • If discomfort, redness or a feeling of heat persists, stop using it and consult a healthcare professional.

Worth remembering: apply this product after toner and before moisturiser, only on the areas concerned, easing in with evening use.

Who might this product suit?

This product could be an option worth considering for people who:

  • Want to improve the look of post-acne marks
  • Are looking to help reduce the look of redness
  • Have excess sebum
  • Want to improve skin texture
  • Have sensitive skin and are looking for a formula tested for that skin type

Conclusion

Post-acne marks, redness and dark spots are among the most common concerns for people with acne-prone skin.

In that context, azelaic acid is often used to help even out the complexion and improve the look of dark spots, while PDRN is valued for its role in maintaining good skin condition and hydration.

For shoppers interested in K-Beauty products that target several concerns at once — hyperpigmentation, redness, excess sebum and uneven skin texture — this formula is one of the options that can be considered, depending on the individual needs of your skin.

Written by: Hyunwoo Lee

Sources

Mary&May Spicule Azelaic PDRN Spot Cream

https://piyonna.com/products/spicule-azelaic-pdrn-spot-cream-15g?_pos=5&_fid=256726856&_ss=c

https://www.beautyaffairs.co.kr/blogs/gybaio/azelaic-acid

https://drelaser.com/sub/acne-solution/acne-pigmentation

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